Amygdalar local structural differences in early- and late-onset Alzheimer's patients
نویسندگان
چکیده
The 3D amygdalar shape was reconstructed with the Radial Atrophy Mapping technique, based on manual segmentations [3]. Shape differences between EOAD and LOAD patients and their age-matched control group were investigated. Permutation testing was used to correct the statistical maps for multiple comparisons [3]. A 3D amygdala model constructed from histological sections was used to infer which anatomical nuclei were involved [4].
منابع مشابه
The role of genetics in alzheimer’s disease
Alzheimer's disease is a progressive neurological disorder that causes the brain to shrink (atrophy) and brain cells die. Alzheimer's disease is the most common cause of dementia and causes a decrease in thinking skills and social behaviors. Alzheimer's disease is more common in people over 65 years old. The risk of developing Alzheimer's disease and other types of dementia increases with age,...
متن کاملMixed handedness is associated with greater age-related decline in volumes of the hippocampus and amygdala: the PATH through life study
Handedness has been found to be associated with structural and functional cerebral differences. Left handedness and mixed handedness also appear to be associated with an elevated risk of some developmental and immunological disorders that may contribute to pathological processes developing in ageing. Inconsistent reports show that left handedness may be more prevalent in early-onset as well as ...
متن کاملEmotion Processing in Patients with Early- and Late-Onset Temporal Lobe Epilepsy
Objective: Temporal Lobe Epilepsy (TLE) can contribute to various emotional symptoms by damaging the temporal lobe. This study aimed at investigating emotion processing in patients with early- and late-onset TLE compared to a healthy group. Methods: In this causal-comparative study, 60 patients with diagnosed TLE were compared to 60 healthy controls to identify emotion processing styles. The d...
متن کاملClinical and Epidemiological Features of Early and Adult Onset Multiple Sclerosis in Hamedan, Iran, 2004–2005
Mazaheri Sh1, Fazlian MM2, Hossein Zadeh A3 1. Assistant Professor, Department of Neurology, Faculty of medicine, Hamedan University of Medical Sciences 2. General practitioner, Specialty and Subspecialty Hospital of Besat, Hamedan University of Medical Sciences 3. General practitioner, Hamedan Health Center Abstract Background: Multiple Sclerosis (MS) is one of the most common causes of chr...
متن کاملAlzheimer's disease: differences in technetium-99m HMPAO SPECT scan findings between early onset and late onset dementia.
OBJECTIVE To compare the HMPAO SPECT cerebral perfusion patterns in early and late onset Alzheimer's disease. METHODS Twenty patients with early onset disease (<65 years) and 44 patients with late onset disease (>65 years) were studied. All patients fulfilled NINCDS-ADRDA clinical criteria and had details of disease severity and length of history at the time of imaging. Technetium-99m HMPAO S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011